The best alternative to ETQ Reliance, now Reliance by Octave, for growing life science teams
Last updated Facts checked
Matrix Quality is the electronic quality management system for medical device and life science companies that have outgrown paper, Word, Excel and SharePoint/Google Workspace. It suits growing teams of 20 to 1,000 people who need an audit-ready, validated QMS without an enterprise price or an enterprise rollout.
Published pricing from €10,000 a year, more than 50 modules, live in 2 to 6 weeks, and our team supports your migration.
For taking a demo with our team.
This comparison is based on publicly available information and user reviews as of 20 October 2026. Features and capabilities may change over time. For the most accurate information, refer to the official Reliance by Octave website. ETQ Reliance is now sold as Reliance by Octave: Hexagon completed the spin off of Octave, which holds the ETQ business, on 28 May 2026.
Common frustrations with ETQ Reliance
What Reliance reviewers report on G2 (629 reviews; the 10 most recent written reviews read 16 October 2026).
New owner, new name
Hexagon spun off a company called Octave, which took the ETQ business with it. The spin off completed on 28 May 2026, and the product is now sold as Reliance by Octave.
Built for large manufacturers
Reliance is built for large, multi-site manufacturers across many industries. The customer stories on its own page come from Kimberly-Clark, Trane and Rheem.
Complex to learn
On G2, 7 of the 10 most recent written Reliance reviews describe the system as complex, unintuitive or slow to learn, with workflows that take several steps and new users who need extra training.
Reports are hard to shape
On G2, 4 of the 10 most recent written reviews say reports and dashboards are hard to shape without extra configuration.
Six months to implement
G2 reviewers put the average time to implement Reliance at 6 months. 2 of the 10 reviews we read raise cost, one asking for clearer pricing by module.
No published price
Octave does not publish a Reliance price. Its page says pricing is a subscription based on users, modules or sites.
What changes when you switch to Matrix Quality
The challenge
Maintain quality and traceability with a simple workflow
- Complex regulatory requirementsFrom FDA and EMA to ISO and GxP standards, maintaining continuous compliance is resource-intensive.
- Data silos and inefficient processesLegacy systems and fragmented documentation make it difficult to ensure data integrity and traceability.
- Audit readinessPreparing for inspections and demonstrating end-to-end control over quality events can stall innovation and slow time-to-market.
- Scalability and global operationsAs organizations grow, managing quality consistently across multiple sites and partners becomes increasingly difficult.
- Traditional QMS validation is complex and resource-intensiveOften requiring extensive documentation, testing, and ongoing maintenance to meet regulatory expectations.
- Conventional QMS implementations are expensiveHigh licensing fees, long deployment timelines, heavy customization, and ongoing IT and support costs add up quickly.
The solution
All-in-one QMS solution managing compliance, quality, and operations
Matrix Quality empowers organizations to streamline compliance, enhance collaboration, and accelerate innovation while maintaining regulatory rigor.
- CompliancePre-configured workflows and templates aligned with FDA 21 CFR Part 11, ISO 13485, and GxP standards.
- Unified PlatformMore than 50 modules in one system, including document control, CAPA, change control, training, supplier management, complaints and audits. Nonconformances and deviations are handled as quality events that feed CAPA.
- Real-Time VisibilityQuality reports and dashboards give quality leaders the numbers they need for management review and continuous improvement.
- Scalable & SecureCloud-based architecture designed to grow with your organization while maintaining strict data security and traceability.
- Reduced validation effortValidated following GAMP 5, covering 21 CFR Part 11, EU Annex 11, ISO 13485 and GxP, so the validation package does not fall on your team.
- Low cost of ownershipPublished pricing from €10,000 a year, live in 2 to 6 weeks, with migration support from our team.
See exactly how the two platforms stack up on the criteria that matter most to regulated quality teams.
Comparison based on publicly available information and user reviews as of 20 October 2026. Features and capabilities may change over time. "Not assessed" means we have not verified the point for ETQ Reliance.
Watch: Why Matrix Quality Is the Best ETQ Reliance Alternative in 2026
The best ETQ Reliance alternative in 2026 is Matrix Quality.
Switching is easy.
Migrate from ETQ Reliance in 4 simple steps
We analyse your ETQ Reliance setup and map it to Matrix Quality workflows.
Our team supports you in migrating documents, CAPA records, audit records and training data from ETQ Reliance, with full traceability.
Workflows, roles and templates configured, with validation following GAMP 5.
Onboarding and training from our team.
Thank you
A member of our team will be in contact within 48 hours.
Stop fighting your quality system.
Start shipping safer products.
Join 500 life science companies worldwide that run quality on Matrix Quality.